EDGE has been installed! Installation of the EDGE for Excel Add-In just requires a few more steps...

To install the EDGE for Excel Add-In:

  1. Open Excel.
  2. From the Tools menu, select Add-Ins.
  3. Click Browse... (Windows) or Select... (Macintosh)
  4. Find EdgeModule.xla, in the same directory as this README file.
  5. Make sure the checkbox next to "EDGE for Excel Add-In" is checked.
  6. Click OK.
  7. After you click OK, the add-in will install a menu entitled "EDGE" and a toolbar button.

To use the EDGE for Excel Add-In:

  1. Open your gene expression data spreadsheet.
  2. Arrange your data as follows: Covariates should be listed at the top of a worksheet, followed by a blank row, followed by the expression data. The image below provides an example, and so does the sample spreadsheet brca_example.xls. Of the visible arrays, 1, 2, and 3 are from individuals with the BRCA1 mutation and 8 and 9 are from individuals with the BRCA2 mutation.
    3. Screenshot of Example Spreadsheet
  3. Select the area containing the covariates, gene names, and data.
  4. From the EDGE menu, select "Analyze with EDGE". Alternately, select the toolbar button: Analyze Data with EDGE
  5. You will see a dialog specifying the range containing covariates, and the cell range containing data. Take a moment to verify the selections. To change the selections, click the button to the right of the range text area.
  6. Click Continue. The screen may flicker as the add-in saves some temporary files. EDGE will start and your data will be automatically loaded.