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Integrated Science Shorts Series 2006-2007

The aim of this monthly series is to present new and developing work and to foster discussion amongst members of our Quantitative and Computation Biology group, in diverse disciplines. Each meeting comprises two 20-minute talks from two different labs with 10 minutes for questions/discussion. Seminars are in Carl Icahn Lab 101 at 4:30pm.

Tuesday, October 17, 2006
Kerwyn Casey Huang / Matt Rockman, Wingreen Lab / Kruglyak Lab
Kerwyn Casey Huang -Polar expeditions: how membranes segregate in rod-shaped bacteria
Matt Rockman - Worms require the snot gene for copulatory plugging

Tuesday, November 21, 2006
Chris Farrell / Justin Kinney, Broach Lab / Callan Lab
Chris Farrell - Identification of phosphorylation sites on signaling proteins in Saccharomyces cerivisiae
Justin Kinney - Precise physical models of protein-DNA interaction from high-throughput data

Tuesday, December 19, 2006
Woojin Kim / Curtis Huttenhower, Michael Hecht Lab / Olga Troyanskaya Lab
Woojin Kim - Sequence Determinants and Inhibition of the Aggregation of the Alzheimer's Abeta Peptide
Curtis Huttenhower - Integration and Functional Analysis of Microarray Data Sets

Tuesday, February 20, 2007
Nir Yakoby / Georgii Bazykin, Stas Shvartsman Lab / Simon Levin Lab
Nir Yakoby - Feedforward control of pattern formation in a developing tissue
Georgii Bazykin - Extensive parallelism in protein evolution

Tuesday, March 20, 2007
Hany Girgis (Tavazoie lab) / Chris Waters (Bassler lab), Tank Lab & Bassler Lab
Girgis: A Post-Genomic Approach to the Genetic Basis of Bacterial Motility
Waters: Quorum Sensing and the second messenger signal, cyclic di-GMP, coordinately regulate biofilm formation in Vibrio cholerae

Tuesday, April 17, 2007
Liang Li / Greg Stephens, Cox Lab and Greg Stephens
The shape of behavior: dimensionality and dynamics in the natural movement of C. elegans (Stephens)
Searching strategies in Dictyostelium (Li)

Tuesday, May 22, 2007
Daniel Dombeck / Melissa Cody, Tank Lab / Groves Lab
Imaging neural population activity in awake behaving mice (Dombeck)
Great Balls of Iron: The Role of Ferritins and DPS Proteins in the Stress Response (Cody)

Tuesday, September 25, 2007
David Hess / Pankaj Mehta, Caudy & Troyanskaya Labs / Wingreen Lab
Large scale discovery of mitochondrial gene function using computation-driven experimentation
What can quantitative analysis teach us about noise-driven switching in genetic networks?

Tuesday, October 16, 2007
David Gresham / Mike Fisher, Botstein Lab / Hecht Lab
Usual and unusual transcription in yeast /Proteins from a designed model proteome rescue E. coli conditional auxotrophs
Tuesday, November 20, 2007
Yun Kyung "Sophia" Kwon / Aster Legesse-Miller, Rabinowitz Lab / Coller Lab
A domino effect in antifolate drug action / The role of microRNAs in the transition between proliferation and quiescence
Tuesday, December 11, 2007
Hannah Seidel / Matt Hibbs, Kruglyak Lab / Troyanskaya Lab
Widespread genetic incompatibility in C. elegans maintained by balancing selection (Seidel) Query-driven search methods for gene expression microarray analysis (Hibbs)
Tuesday, February 19, 2008
Michael Desai / Kelly McCarthy, Lewis-Sigler Fellow / Enquist Lab
Detecting Directional Selection from the Polymorphism Frequency Spectrum (Desai)
The effects of herpesvirus infection on neuronal electrophysiology (McCarthy)

Tuesday, March 25, 2008
Maitreya Dunham & Chris Bristow, Lewis-Sigler Fellow / Shvartsman Lab
Functional annotation of a novel yeast genome by a computer-controlled army of undergraduates (Dunham)
A combinatorial code for epithelial patterning by interacting signaling pathways (Bristow)

Tuesday, April 15, 2008
Zia Khan / Carey Nadell, Singh & Kruglyak Labs / Bassler Lab
Data! Too much data! Measuring Transcript Abundance by High Throughput Sequencing and Protein Abundance by High Resolution Mass Spectrometry (Khan)
Social evolution in bacterial biofilms (Nadell)

Tuesday, May 20, 2008
Sasan Amini / Ethan Perlstein, Tavazoie Lab / Lewis-Sigler Fellow
Genetic Dissection of an Exogenously-Induced Biofilm in Laboratory and Clinical Isolates of E. coli (Amini) / Assessing the evolutionary conservation of therapeutic drug action in yeast (Perlstein)



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