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Lewis-Sigler Institute Seminar Archive Quantitative and Computational Biology Seminar Series 2007-2008 Monday, April 28, 2008 Catherine L. Peichel , Fred Hutchinson Cancer Research Center Genetics of reproductive isolation in sticklebacks Monday, April 21, 2008 Fabio Piano , Center for Genomics and Systems Biology, Department of Biology, New York University C. elegans early development: global, local and evolutionary views Monday, April 14, 2008 Eran Segal , Weizmann Institute of Science Towards Quantitative Models for Transcription and Chromatin Regulation Monday, April 07, 2008 Gregory J. Hannon , Cold Spring Harbor Laboratory Conserved roles of small RNAs in genome defense Monday, March 31, 2008 Claire M. Fraser-Liggett , University of Maryland School of Medicine Understanding human microbial diversity through metagenomics Monday, March 24, 2008 Oliver Rando , University of Massachusetts Static and dynamic genome-wide views of yeast chromatin Monday, March 10, 2008 Drew Endy , Massachusetts Institute of Technology Department of Biological Engineering Reliable design and operation of natural and engineered biological systems Monday, March 03, 2008 Eva Nogales , HHMI / UC Berkeley Visualizing self-assembly processes essential in cell division Monday, February 25, 2008 Steven Gygi , Harvard Medical School Protein Phosphoryation and Mass Spectrometry Monday, February 18, 2008 Mark Boguski, M.D., Ph.D. , Former Vice President and Global Head, Genome and Proteome Sciences, Novartis Institutes for Biomedical Research Proteomics, Systems Biology and Knowledge-mining in Drug and Biomarker Discovery Monday, February 04, 2008 Christina D. Smolke , California Institute of Technology A framework for programming system behavior through integrated RNA devices Monday, December 17, 2007 CANCELLED - Guri Giaever , University of Toronto CANCELLED Monday, December 10, 2007 Helen H. Hobbs , Howard Hughes Investigator, University of Texas Southwestern Medical Center Going to extremes to identify genetic variation contributing to heart disease Monday, December 03, 2007 Cori Bargmann, Ph.D. , The Rockefeller University Dissecting a sensory circuit for olfactory behavior Monday, November 19, 2007 H. Alex Brown , Departments of Pharmacology and Chemistry, Vanderbilt University School of Medicine Lipidomics and Cell Signaling Networks Monday, November 12, 2007 David Altshuler MD, PhD , Harvard Medical School, Massachusetts General Hospital & Broad Institute of Harvard and MIT Human genome variation and the inherited basis of disease Monday, November 05, 2007 Patrick O. Brown , Howard Hughes Medical Institute / Stanford Department of Biochemistry Searching for the “dark matter” of biological regulation Monday, October 22, 2007 Arend Sidow , Stanford University Functional architecture of cis elements that drive gene (co)expression Monday, October 15, 2007 Elizabeth Winzeler , Scripps Research Institute Genome-scale genetics of host pathogen interactions Monday, October 08, 2007 Steven E. Brenner , University of California, Berkeley Ultraconserved nonsense: Pervasive unproductive splicing of SR proteins associated with exceptionally conserved DNA elements -- a bizarrely prevalent Byzantine mode of gene regulation. Monday, October 01, 2007 Erik Winfree , California Institute of Technology Synthetic transcriptional networks in vitro Monday, September 24, 2007 Katherine S. Pollard , UC Davis Genome Center & Department of Statistics Accelerated and biased nucleotide evolution in the human lineage Quantitative and Computational Biology Seminar Series 2006-2007 Monday, April 23, 2007 Audrey Gasch , University of Wisconsin - Madison Genomic approaches to studying stress defense in yeast Monday, April 16, 2007 Ray Keller , University of Virginia Mechanisms of Emergent Morphogenic Specificity During Gastrulation Monday, April 09, 2007 John Yates , The Scripps Research Institute Driving Biological Discovery using Mass Spectrometry Monday, April 02, 2007 Philip N Benfey , Duke University Biology Department / Institute for Genome Sciences and Policy A systems approach to understanding organ development Monday, March 26, 2007 Leslie Vosshall , The Rockefeller University Olfaction: From Receptors to Perception Monday, March 12, 2007 Garrett M. Odell , Center for Cell Dynamics, University of Washington Using agent-based computer simulations ruled by differential equations to understand cytoskeletal dynamics Monday, March 05, 2007 Brenda Andrews , Banting & Best Department of Medical Research, Terrence Donnelly Centre for Cellular & Biomolecular Research, University of Toronto Systematic yeast genetics to explore biological pathways, gene toxicity and kinase targets Monday, February 26, 2007 Tom Maniatis , Harvard University, Department of Molecular and Cellular Biology Regulation of Transcription and pre-mRNA Splicing by Brain-Specific micro RNAs Monday, February 19, 2007 Justin Borevitz , Ecololgy & Evolution, University of Chicago Genomic responses underlying the genetics of adaptation Monday, February 12, 2007 Andrew Murray , Harvard University Yeast and Evolution: Experiment and Theory Monday, February 05, 2007 Peter van Haastert , University of Groningen, Netherlands Chemotaxis in Dictyostelium: signals for biased random walk and directional movement Monday, December 11, 2006 Michael Eisen , Lawrence Berkeley National Lab (LBNL) & University of California at Berkeley Understanding and exploiting the evolution of eukaryotic regulatory sequences Monday, December 04, 2006 Carl Pabo, Harvard Medical School Structure and Design of DNA-Binding Proteins Monday, November 27, 2006 Justin Fay , Department of Genetics - Washington University Evolution of gene regulation and misregulation Monday, November 20, 2006 Mona Singh , Princeton University/Lewis-Sigler Institute & Department of Computer Science Analyzing and interrogating interaction networks Monday, November 13, 2006 John Tyson , Department of Biological Sciences and the Virginia Bioinformatics Institute, Virginia Tech Network Dynamics and Cell Physiology Monday, November 06, 2006 Martha Bulyk , Brigham & Women's Hospital and Harvard Medical School Genomic Analyses of Transcription Factors and Cis Regulatory Elements Monday, October 23, 2006 Roy Kishony , Harvard Medical School Functional classification in gene and drug networks Monday, October 16, 2006 Claude Desplan , New York University Department of Biology Evolution of axis formation in insects Monday, October 09, 2006 Dana Pe'er , Columbia University, Biological Sciences Genetic Variation and Regulatory Networks: Mechanisms And Complexity Monday, September 25, 2006 David C Page , Director, Whitehead Institute / MIT / HHMI Is Retinoic Acid a Sex Hormone? Quantitative and Computational Biology Seminar Series 2005-2006 Monday, May 08, 2006 Jonathan Weissman , University of California, San Francisco Dissecting the Functional and Organization Principles of Cells through Epistatic MiniArray Profiles (EMAPs) Monday, May 01, 2006 Douglas Koshland , Carnegie Institution of Washington / HHMI Lessons learned from the oxymoron, yeast chromosome structure Monday, April 24, 2006 David Dubnau , Public Health Research Institute Cell type-specific and temporal control of competence gene expression in Bacillus Monday, April 17, 2006 Dan Herschlag , Stanford University The Logic of Gene Expression: A Global View of RNA Processing Monday, April 10, 2006 Aviv Regev , Harvard University / Bauer Center Trees and Forests: How do molecular networks accommodate change? Monday, April 03, 2006 Jose Onuchic , University of California, San Diego The Energy Landscape for Folding and Function Monday, March 13, 2006 Douglas Lauffenburger , Massachusetts Institute of Technology What Are Cells “Thinking”? (And How Might We Think About This…?) Monday, March 06, 2006 Marcello Magnasco , Rockefeller University The dynamical basis of auditory acuity Monday, February 27, 2006 Tom Gingeras (replaces Stephen Fodor) , Affymetrix, Inc Transcriptional Landscape of Human Genome: Lessons Forgotten and Relearned Monday, February 20, 2006 Daphne Preuss , University of Chicago/HHMI Mating Specificity in Arabidopsis and its Relatives: Navigating the Pollination Pathway Monday, February 13, 2006 Jason Lieb , University of North Carolina Chapel Hill Chromatin Context and DNA Binding-Site Utilization Monday, December 12, 2005 Gary Churchill , Jackson Laboratory Coadapted alleles and the evolution of complex traits Monday, December 05, 2005 William H Press , Los Alamos National Laboratory Isochores and 3' UTRS: AT- and CG-rich Genes Are Functionally Different Monday, November 28, 2005 David Stern , Princeton University Department of Ecology & Evolutionary Biology Does genomic complexity make genetic evolution predictable? Monday, November 21, 2005 Mats Gustafsson, University of California San Francisco Light microscopy with theoretically unlimited resolution Monday, November 14, 2005 David Baker , University of Washington Prediction and design of macromolecular structures and interactions Monday, November 07, 2005 Sebastian Seung , Massachusetts Institute of Technology Of songs and synapses: modeling the neural basis of birdsong Monday, October 24, 2005 Boris Shraiman , Kavli Institute for Theoretical Physics / UCSB Physical aspects of growth control in development Monday, October 17, 2005 Manolis Kellis , Massachusetts Institute of Technology Computational genomics in yeast and human: genes, regulation, evolution Monday, October 10, 2005 William Bialek , Princeton University Department of Physics & Lewis-Sigler Institute Maximum entropy models for biological networks Monday, September 26, 2005 Lew Cantley , Harvard Medical School Cell Growth Regulation Quantitative and Computational Biology Seminar Series 2003-2005 Monday, April 25, 2005 Bernard O. Palsson (This seminar is at 12:30pm) , University of California, San Diego New "Dimensions" in Genome Annotation Monday, April 18, 2005 Dan Gottschling , Fred Hutchinson Cancer Research Center Nuclear incontinence: The effects of old age on the genome Monday, April 11, 2005 Timothy Hughes , University of Toronto The functional landscape of gene expression in yeast and mouse Monday, April 04, 2005 Art Owen , Stanford University Kidneys, Aging, and False Discoveries Monday, March 21, 2005 Karel Svoboda , Cold Spring Harbor Laboratory/HHMI Imaging experience-dependent synaptic plasticity in vivo Monday, March 07, 2005 Sean Eddy , Washington University School of Medicine The modern RNA world: computational analysis of noncoding RNAs Monday, February 28, 2005 Adam Arkin , Lawrence Berkeley National Laboratory Stochastic Switching in HIV-1 derived Lentiviral Systems: Implications for Latency and Lentiviral-based Therapies Monday, February 21, 2005 Tom Petes , University of North Carolina, Chapel Hill Genetic regulation of genome stability in yeast Monday, February 07, 2005 Nancy Kleckner , Harvard University Chromosomes as mechanical objects: hints from mitosis, meiosis and E.coli Monday, November 29, 2004 Chris Sander , Memorial Sloan-Kettering Cancer Center microRNAs and Pathways Monday, November 22, 2004 Fritz Roth , Harvard Medical School A network analysis of synthetic lethality in yeast Monday, November 15, 2004 James Ferrell , Stanford University School of Medicine Deconstructing the mitotic oscillator Monday, November 8, 2004 Lew Cantley , Harvard Medical School Seminar cancelled. Monday, November 01, 2004 Stan Leibler , Rockefeller University Are bacteria individuals? (And why should we care???) Monday, October 18, 2004 Yoshikazu Ohya, University of Tokyo Functional Genomics in S. cerevisiae: Global and Quantitative Analysis of Cell Morphology Monday, October 11, 2004 Alan Perelson , Los Alamos National Laboratory Modeling HIV: Drug Therapy, Immune Responses and Vaccination Monday, September 27, 2004 Steve Quake , California Institute of Technology Biological Large Scale Integration. Monday, September 20, 2004 Naama Barkai , Weizmann Institute of Science The interplay between transcription network design and growth phenotype in S. cerevisiae and other yeast species Monday, May 03, 2004 Charles Boone, University of Toronto Genetic Interaction Networks: Global Mapping of Functional Relationships Amongst Genes and Pathways in Yeast Monday, November 24, 2003 Leonid Kruglyak, Fred Hutchinson Cancer Center Genome-wide Mapping of Regulatory Variation in Yeast: A Simple Model System for Complex Genetics Monday, November 03, 2003 Philippe Cluzel, University of Chicago Noise, networks, and adaptation in simple biological systems Monday, October 20, 2003 Felix Naef , Rockefeller University A Probabilistic Approach to Dissect Drosophila Monday, October 13, 2003 Leonid A Mirny , Massachusetts Institute of Technology Discovering protein complexes and modules in molecular networks Monday, September 29, 2003 Charles M. Perou, Ph.D. , Lineberger Comprehensive Cancer Center Molecular Portraits of Human Tumors Monday, September 22, 2003 Dr. Anirvan Sengupta , Rutgers University A Biophysical Approach to Transcription Factor Binding Site Discovery Other Seminars at the Institute 2004-2007 Tuesday, May 13, 2008 Katharina Ribbeck , Harvard University FAS Center for Systems Biology From nuclear pores to mucus - a study of hydrogel-based biofilters Monday, April 28, 2008 Timothy Newman , Arizona State University Fluctuation-induced cycling and spatio-temporal feedback in biological systems Monday, April 21, 2008 John O. Dabiri , California Institute of Technology The role of fluid forces in aquatic animal morphogenesis Monday, April 14, 2008 Tony Dean , University of Minnesota Experiments in Evolutionary History Tuesday, April 08, 2008 Allan Drummond '95 , Harvard University FAS Center for Systems Biology Ribosomal infidelity, protein misfolding, and gene evolution (AT PRINCETON) Monday, April 07, 2008 Phillip Geissler , University of California, Berkeley Dynamics of Biomolecular Organization, and Disorganization, at the Nanometer Scale Monday, March 31, 2008 Steven Gross , University of California, Irvine Title to be announced... Monday, March 24, 2008 Eric Lauga , University of California, San Diego Hydrodynamics and cell motility Friday, March 07, 2008 William Ryu , Lewis-Sigler Institute Fellow Thermal responses and motor behavior of E. coli and C. elegans Tuesday, February 12, 2008 Marcus R. Kronforst , Harvard University FAS Center for Systems Biology Exploring the genetic basis of mimicry and speciation in Heliconius butterflies Friday, January 18, 2008 Joshua Rabinowitz speaks at Harvard , Princeton University / Lewis-Sigler Institute Center for Quantitative Biology AT HARVARD - Towards a comprehensive understanding of cellular metabolism Tuesday, December 04, 2007 Kevin Verstrepen , from the FAS Center for Systems Biology, Harvard University Tandem repeats as hypervariable genetic modules: Bridging the gap between genetics and epigenetics Friday, November 16, 2007 Maitreya Dunham , from the Lewis-Sigler Institute/Princeton University Genomic analysis of experimental evolution in yeasts Tuesday, October 02, 2007 Suckjoon Jun , from the FAS Center for Systems Biology, Harvard University Can entropy save bacteria? Tuesday, August 14, 2007 Link for Schedule , Various August 14 & 15 - Integrating Genetics, Genomics, and Education: a symposium celebrating David Botstein's 65th birthday Wednesday, May 10, 2006 Erling Norrby , Center for the History of Sciences - The Royal Swedish Academy of Sciences Over One Hundred Years of Nobel Prizes. Dr. Erling Norrby has been a Professor of Virology and Dean at the Karolinska Institute. He then served as Secretary General of the Royal Swedish Academy of Sciences and is currently at its Center for the History of Sciences. Dr. Norrby has a long history of involvement with the Nobel Prizes in Natural Sciences and has been a member of the Board of the Nobel Foundation. He is a member of the American Philosophical Society. In his seminar he will talk about Alfred Nobel and his family, the formation of the Foundation, and the different Prizes. Dr. Norrby will discuss the secrecy and process of selection of the Prizes, and what Nobel Prizes tell us about creative milieus. Tuesday, February 28, 2006 Maria Neimark Geffen, Harvard University Program in Biophysics Active Sensation and Processing of Complex Stimuli In Early Sensory Systems Thursday, February 16, 2006 John Storey , University of Washington High-Dimensional Analysis of Functional Genomic Data Tuesday, February 07, 2006 Robert Bao, CalTech A microfluidic platform for cell signaling experiment Monday, February 06, 2006 Erez Dekel, Weizmann Institute of Science Optimality and evolutionary tuning of the expression level of a protein Thursday, June 09, 2005 Tim Stearns , Stanford University Yeast Genomics - An Ames Test for the 21st Century? Friday, May 13, 2005 Michael Desai, Harvard University Department of Physics The Speed of Evolution and Maintenance of Variation in Asexual Evolution Thursday, April 14, 2005 Sydney Kustu, University of California, Berkeley The Discovery of biological gas channels: evidence that the Rh(Rhesus) proteins are gas channels for CO2 BACK TO TOP Last updated: Copyright © 2007 Lewis-Sigler Institute for Integrative Genomics. Princeton University. All Rights Reserved.